What's New, Aurora Denver Cardiology Associates, Colorado

Heart Rhythm

The role of chronic atrial stretch and atrial fibrillation on posterior left atrial wall conduction

Background: The posterior left atrium (LA) is involved in the initiation and maintenance of atrial fibrillation (AF).Objective: The purpose of this study was to compare conduction patterns on the posterior LA in patients with mitral reg... [+]

?Zooming in? to new horizons: Conduction abnormalities and other research perspectives in atrial fibrillation

Despite recent improvements in the understanding, diagnosis, and treatment of atrial fibrillation (AF), the arrhythmia and its consequences remain a major unresolved problem of modern cardiology. AF is associated with a do... [+]

Mechanisms of the maintenance of atrial fibrillation: Role of the complex fractionated atrial electrogram assessed by noncontact mapping

Background: The role of complex fractionated atrial electrograms (CFAEs) in the maintenance of atrial fibrillation (AF) has not been well clarified.Objective: The purpose of this study was to examine... [+]

Heart rate, pacing, and outcome in the Dual Chamber and VVI Implantable Defibrillator (DAVID) trials

Background: Slower heart rates are believed to confer a better prognosis in heart disease. The Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial found that patients with ventricular dysfunction and isolated sinus bradycardia... [+]

Implantable cardioverter-defibrillator prescription in the elderly

Background: Because sudden cardiac death increases with age, implantable cardioverter-defibrillators (ICDs) might greatly benefit the elderly. However, elderly patients are underrepresented in clinical trials, and comorbid conditions may attenuate benefit.Objective: Th... [+]

?Low ejection fraction prophylaxis? with implantable defibrillators in the elderly: Call for a randomized trial?

MADIT-II (Multicenter Automatic Defibrillator Implantation Trial-II) and SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) were landmark studies because they demonstrated the survival benefit of prophylactic device... [+]

Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation

Background: Mutations in several ion channel genes have been reported to cause rare cases of familial atrial fibrillation (AF).Objective: The purpose of this study was to determine the genetic basis for AF in a family with autosomal dominant AF.Methods: F... [+]

Kv7.1 in atrial fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia. It affects more than two million Americans today, and the number is estimated to increase to more than four million by 2020. AF is associated with increased prevalence of stroke, heart failure, and death. The causes of AF are diverse and inclu... [+]

Role of signal-averaged electrocardiograms in arrhythmic risk stratification of patients with Brugada syndrome: A prospective study

Background: Arrhythmic risk stratification in patients with Brugada syndrome remains controversial. Several recent reports have highlighted the possible role of late potential (LP) on the signal-averaged ... [+]

Abnormal transmural repolarization process in patients with Brugada syndrome

Background: Repolarization abnormality, especially during bradycardia, might be critical for initiation of ventricular fibrillation (VF) in patients with Brugada syndrome (BrS), but the contribution of the rate-dependent repolarization dynamics to the occurre... [+]